SmartDrug

Nootropics

NootropicsPrimer

Notes on Nootropics with evidence

Key resources

Studies on effectiveness of various Nootropics

Other notes

Caffeine

Ginseng

The information below is uncited - it would be good to collect links to specific studies to help assess which might be effective. ThufirHawat Citations are being added. *

I advise reading them because I'm trying to include both supporting and detracting articles. Also, where info is sparse I include animal studies, and pathological studies - CassoX

Racetam Groups

AgentMechanismEffectDosageCitations
Piracetammechanismeffect1600 mg - 9600 mg[5][6][7][8][9][10]
Aniracetammechanismeffect750 mg - 1500 mg[11][12][13][14][15]
Oxiracetammechanismeffect800mg - 1600mg[16][17][18][19][20][21]
Nefiracetammechanismeffectdosage[22]
Pramiracetammechanismeffect200 mg - 400 mg[23]
Phenylpiracetampoorly characterizedantiamnesia, psychostimulatory effect100-200mg[24] [25]



Inhibitors

AgentMechanismEffectDosageCitations
Huperzine AInhibits Acetylcholinesterase
Increases Acetylcholine levels
effect50 mcg - 200 mcg[26]
VinpocetineInhibits Phospodiesterases
Increases levels of cAMP, cGMP
effect5 mg - 10 mg[27]
GalantamineInhibits Acetylcholinesterase
Increases Acetylcholine levels
EffectDosagesource
L-DeprenylInhibits MAO-B
Increases Dopamine Levels
EffectDosagesource
TolcaponeInhibits COMT
Increases Dopamine Levels
Increases Epinephrine levels
Increases Norepinephrine Levels
EffectDosagesource
2C-EInhibits MAO-B
Increases Serotonin
Stimulant at low dosesDose:5-10mgsource



Neuroreceptor Agents

AgentMechanismEffectDosageCitations
HydergineStimulates dopaminergic and seratonergic receptors
Inhibits Alpha Adrenoceptors
Increases MAO levels
effectdosagesource



Neurotransmitter Precursors

AgentMechanismEffectDosageCitations
5-HTPNeurotransmitter precursor for Serotonin
Increases serotonin levels
effectdosagesource
DMAENeurotransmitter precursor for choline
Increase Acetylcholine Levels
effectdosagesource
CentrophenoxineNeurotransmitter precursor for choline
Increases acetylcholine levels
Reduces Lipofuscins
effectdosagesource
Acetyl-L-CarnitineNeurotransmitter Precursor for AcetylcholineEffectDosagesource
Alpha-GPCNeurotransmitter Precursor for CholineEffectDosagesource
Choline CitrateNeurotransmitter Precursor for AcetylcholineEffectDosagesource
Choline BitartrateNeurotransmitter Precursor for AcetylcholineEffectDosagesource
CiticolineMechanismEffectDosagesource



Stimulants

StimulantsPrimer?

AgentMechanismEffectDosageCitations
CaffeineMechanismEffectDosagesource
RitalinMechanismEffectDosagesource
AdderalMechanismEffectDosagesource
ModanifilMechanismEffectDosage[28]
EphedraMechanismEffectDosagesource



Essential Nutrition

NutrientsPrimer?

Amino Acids

Essential

Amino AcidFunctionDosageCitations
IsoleucineFunctionDosagesource
LeucineFunctionDosagesource
LysineFunctionDosagesource
MethionineFunctionDosagesource
PhenylalanineFunctionDosagesource
ThreonineFunctionDosagesource
TryptophanFunctionDosagesource
ValineFunctionDosagesource
ArginineFunctionDosagesource
HistidineFunctionDosagesource

Nonessential

Amino AcidFunctionDosageCitations
AlanineFunctionDosagesource
AsparagineFunctionDosagesource
AspartateFunctionDosagesource
CysteineFunctionDosagesource
GlutamateFunctionDosagesource
GlutamineFunctionDosagesource
GlycineFunctionDosagesource
ProlineFunctionDosagesource
SerineFunctionDosagesource
TyrosineFunctionDosagesource

Nonstandard

Amino AcidFunctionDosageCitations
L-DopaNeurotransmitter Precursor for Dopamine
Increases Dopamine Levels
Dosagesource

Essential Fatty Acids


Essential Vitamins

AgentMechanismEffectDosageCitations
Pantothenic AcidMechanismEffectDosagesource


Essential Minerals


Miscellaneous


AgentMechanismEffectDosageCitations
Ginko BilobaMechanismEffectDosagesource
GinsengMechanismEffectDosagesource
Mucuna PruriensMechanismEffectDosagesource
YohimbeMechanismEffectDosagesource